Medications
Medication does not cure
asthma. But it is an important part of managing the
condition. Medications for asthma treatment are used to:
- Prevent and control the underlying airway
inflammation
, to minimize asthma symptoms.
- Decrease the severity, frequency, and duration of
asthma attacks.
- Treat the attacks as they
occur.
Asthma medications are divided into two groups: those for
prevention and long-term control of
inflammation
and those that provide quick relief for
asthma attacks. Most people with
persistent asthma need to use long-term medications
daily. Quick-relief medications are used as needed and provide rapid relief of
symptoms during asthma attacks.
Because asthma develops from a complex interaction of genetics,
environmental factors, and the reaction of the
immune system, different people may use different
medications and doses of medications. Special consideration may be necessary if
you:
- Are pregnant. If a woman had asthma
before becoming pregnant, her symptoms may become better or worse during
pregnancy. Pregnant women whose asthma is not well controlled may be at risk
for a number of complications.
- Are an older adult.
Older adults tend to have worse asthma symptoms and a higher risk of death from
asthma than younger people. They may also have one or more other health
conditions or take other medications that can make asthma symptoms
worse.
- Have exercise-induced asthma. Exercise often causes
asthma symptoms. Steps you can take to reduce the risk of this include using
medication immediately before you exercise.
- Need surgery. People
with moderate to severe asthma are at higher risk than people who do not have
asthma of developing problems during and after surgery.
Medication delivery
Most medications for asthma are inhaled. Inhaled medications are
used because a specific dose of the medication can be given directly to the
bronchial tubes. Different types of
delivery systems may be used to do this, and one type
may be more suitable for certain people or age groups than another. Delivery
systems include metered-dose and dry powder
inhalers. A metered-dose inhaler is used most
often.
Most health professionals recommend that everyone who uses a
metered-dose inhaler (MDI) also use a
spacer
, which is attached to the MDI. A spacer may
deliver the medication to your lungs better than an inhaler alone, and for many
people it is easier to use than an MDI alone. Using a spacer with inhaled
corticosteroids can help reduce their side effects and
result in less use of oral corticosteroids.
It is important to keep track of the inhaler doses and discard
the inhaler when you have used the number of doses indicated on the package
labelling. This not only prevents you from having an empty inhaler when you
need medication, but it also prevents you from inhaling only propellant after
the medication has run out. For more information, see:
Using a metered-dose
inhaler.
Using a dry powder inhaler.
Medication Choices
The most important asthma medications are:
- Inhaled corticosteroids. These are the
preferred medications for long-term treatment of asthma. They reduce
inflammation of your airways and are taken every day to keep asthma under
control and to prevent sudden and severe symptoms (asthma
attacks). Inhaled corticosteroids include beclomethasone dipropionate,
fluticasone propionate, budesonide, and ciclesonide (Alvesco).
- Oral or injected corticosteroids (systemic
corticosteroids) to get your asthma under control before you start taking daily
medication. You may also need these medications to treat asthma attacks. Oral
corticosteroids are used much more than injected corticosteroids. Oral
corticosteroids include prednisone and dexamethasone.
- Fast-acting beta2-agonists for asthma attacks. They
relax the airways, allowing you to breathe easier. These medications include
salbutamol and terbutaline.
Other long-term medications for daily treatment include:
Other medications may be given in some cases.
- Anticholinergics (such as ipratropium)
and magnesium sulfate are usually used for severe asthma
attacks.
- Other medicine such as
omalizumab may be used if asthma does not improve with
treatment. An asthma specialist generally prescribes this medicine.
See a
chart
of asthma medications for teens and adults.
What to Think About
Medications are usually added one at a time to keep the number of
medications low. The dosage of each medication should correspond to the
severity of your asthma. Sometimes your health professional will start you at a
higher dose within your asthma
classification so that the inflammation is immediately
controlled. After a prolonged period of symptom improvement, the dose of the
last medication added is reduced to the lowest possible dose for maintenance.
This is known as step-down care. Step-down care is believed to be a better way
to control inflammation in the bronchial tubes than starting at lower doses of
medication and increasing the medication if the dose is not enough.19
Because quick-relief medication quickly reduces symptoms, people
sometimes overuse these medications instead of using the slower-acting
long-term medications. But
overuse of quick-relief medications may have harmful
effects, such as decreasing the future effectiveness of these
medications.20 Overuse of quick-relief medication is
also an indication that asthma symptoms are not being controlled. If you need
to use your quick-relief medication more than twice a week, be sure to talk
with your health professional immediately.
You may have to take many different medications daily to manage
your asthma. It can be difficult to remember when to take your medication and
which medication to take. To help yourself remember, understand the reasons
people don't take their asthma medications, and then find
ways to overcome those obstacles, such as taping a
note to your refrigerator to remind yourself.
Using the fewest medications possible is important for older
people, because they may be taking medications for other conditions. Tell your
health professional about all the medications you are taking, so he or she can
select asthma medications that won't interfere with other medicines.
Some people only have symptoms during certain times of the year
(seasonal asthma). If you know when you will most likely have symptoms, start
using a medication to decrease inflammation before the symptoms start.