Gastrin

Test Overview

A gastrin test measures the level of the hormone gastrin in the blood. Gastrin is produced by cells called G cells in the stomach lining. When food enters the stomach, G cells trigger the release of gastrin in the blood. As blood levels of gastrin rise, the stomach releases acid (gastric acid) that helps break down and digest food. When enough gastric acid has been produced by the stomach, gastrin levels in the blood drop.

Gastrin also has minor effects on the pancreas, liver, and intestines. Gastrin helps the pancreas produce enzymes for digestion and helps the liver produce bile. It also stimulates the intestines to help move food through the digestive tract.

Sometimes a test for gastrin is done after eating a high-protein diet or after receiving an injection of the digestive hormone secretin into a vein. This is called an intravenous secretin test.

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Author:	Douglas Dana Sydney Youngerman-Cole, RN, BSN, RNC	Last Updated: June 27, 2006
Medical Review:	Martin Gabica, MD - Family Medicine Adam Husney, MD - Family Medicine Jerome B. Simon, MD, FRCPC, FACP - Gastroenterology
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