Chloride (Cl)

Test Overview

A chloride test measures the level of chloride in your blood or urine. Chloride is one of the most important electrolytes in the blood. It helps keep the amount of fluid inside and outside of your cells in balance. It also helps maintain proper blood volume, blood pressure, and pH of your body fluids. Tests for sodium, potassium, and bicarbonate are usually done at the same time as a blood test for chloride.

Most of the chloride in your body comes from the salt (sodium chloride) you eat. Chloride is absorbed by your intestinesClick here to see an illustration. when you digest food. Extra chloride leaves your body in your urine.

Sometimes a test for chloride can be done on a sample of all your urine collected over a 24-hour period (called a 24-hour urine sample) to find out how much chloride is leaving your body in your urine.

Chloride can also be measured in skin sweat to test for cystic fibrosis.


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Author: Carrie Henley
Sydney Youngerman-Cole, RN, BSN, RNC
Last Updated: August 1, 2006
Medical Review: Martin Gabica, MD - Family Medicine
Adam Husney, MD - Family Medicine
Tom Bailey, MD - Family Medicine

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Topic Contents
Arrow PointerTest Overview
 Why It Is Done
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 How It Is Done
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 What Affects the Test
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