Mononucleosis Tests

EBV Antibody Test, Epstein-Barr Antibody Test, Monospot Test

What To Think About

  • Since many people are exposed to Epstein-Barr virus (EBV) during childhood, most adults have EBV antibodies of a type called IgG. The presence of the IgG type of antibody does not mean that you have had a recent infection with EBV.
  • Rapid diagnostic tests for mono are not useful for children younger than 4 years.
  • Although some people think that the Epstein-Barr virus (EBV) may be related to chronic fatigue syndrome (CFS), experts have found no evidence for this. The monospot test and the EBV antibody test are not used to diagnose or monitor CFS.
  • Children, especially those younger than 2 years, are more likely than adults to have a negative monospot test, even when they have mono. This is called a false-negative result.

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Author: Douglas Dana
Maria G. Essig, MS, ELS
Last Updated: February 21, 2008
Medical Review: Anne C. Poinier, MD - Internal Medicine
Michael J. Sexton, MD - Pediatrics
W. David Colby IV, MSc, MD, FRCPC - Infectious Disease

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Topic Contents
 Test Overview
 Why It Is Done
 How To Prepare
 How It Is Done
 How It Feels
 Risks
 Results
 What Affects the Test
Arrow PointerWhat To Think About
 References
 Credits