Prolactin

Lactogenic Hormone

Results

A prolactin test measures the level of the hormone prolactin, which is made by the pituitary gland, in your blood. Prolactin levels are different throughout the day. The highest levels occur during sleep and shortly after you wake up.

Normal

Normal values may vary from lab to lab.

Prolactin
Non-pregnant women

Less than 25 micrograms per litre (mcg/L) (SI units) or 25 nanograms per millilitre (ng/mL)

Men

Less than 20 mcg/L (SI units) or 20 ng/mL

Pregnant women

20 to 400 mcg/L (SI units) or 20 to 400 ng/mL

High values

  • High levels of prolactin (usually higher than 200 mcg/L) may mean a pituitary gland tumour (prolactinoma) is present. The higher the prolactin level, the more likely a pituitary gland tumour is present. If a prolactin level is over 200 mcg/L, a magnetic resonance imaging (MRI) test may be done to confirm a pituitary tumour is present. A normal or low prolactin level does not always mean there is no pituitary tumour. An MRI test may be done if a pituitary tumour is suspected.
  • High levels of prolactin may mean that the pituitary gland is making excess prolactin for unknown reasons (idiopathic hyperprolactinemia).
  • Other conditions that can cause high prolactin levels include pregnancy, liver disease (cirrhosis), kidney disease, and hypothyroidism.

Many conditions can affect prolactin levels. Your health professional will talk with you about any abnormal results in relation to your symptoms and medical history.


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Author: Carrie Henley
Jan Nissl, RN, BS
Last Updated: September 26, 2006
Medical Review: Renée M. Crichlow, MD - Family Medicine
Tom Bailey, MD - Family Medicine
Kirtly Jones, MD - Obstetrics and Gynecology

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Topic Contents
 Test Overview
 Why It Is Done
 How To Prepare
 How It Is Done
 How It Feels
 Risks
Arrow PointerResults
 What Affects the Test
 What To Think About
 References
 Credits