Cancer Antigen 125 (CA-125)

CA-125 (Cancer Antigen) Test, Carbohydrate Antigen (CA-125) Test

What To Think About

  • The cancer antigen 125 (CA-125) test cannot tell the difference between a cancerous (malignant) or non-cancerous (benign) ovarian lump.
  • The test for CA-125 may also be done on body fluids (other than blood) taken from the chest or stomach area.
  • High values of CA-125 in a woman who has been treated for ovarian cancer may mean that the cancer has returned. Often the high CA-125 level is found many months before the return of cancer can be found in another way.
  • Studies are being done to see if CA-125 can be used as a screening test for ovarian cancer. So far, there is not enough proof to show that this test works to find ovarian cancer early.

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Author: Maria G. Essig, MS, ELSLast Updated: August 15, 2007
Medical Review: Adam Husney, MD - Family Medicine
Anne C. Poinier, MD - Internal Medicine
Douglas A. Stewart, MD - Medical Oncology

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Topic Contents
 Test Overview
 Why It Is Done
 How To Prepare
 How It Is Done
 How It Feels
 Risks
 Results
 What Affects the Test
Arrow PointerWhat To Think About
 References
 Credits