Test Overview
The sedimentation rate (sed rate) blood test measures how quickly
red blood cells (erythrocytes) settle in a test tube in one hour. The more red
cells that fall to the bottom of the test tube in one hour, the higher the sed
rate.
When
inflammation is present in the body, certain
proteins cause red blood cells to stick together and
fall more quickly than normal to the bottom of the tube. These proteins are
produced by the liver and the
immune system under many abnormal conditions, such as
an infection, an
autoimmune disease, or cancer.
There are many possible causes of a high sedimentation rate. For
this reason, a sed rate is done with other tests to confirm a diagnosis. Once a
diagnosis has been made, a sed rate can be done to help check on the
disease or see how well treatment is working.