Test Overview
A lymph node
biopsy removes
lymph node tissue to be looked at under a microscope
for signs of infection or a disease, such as cancer. Other tests may also be
used to check the lymph tissue sample, including a
culture, genetic tests, or tests to study the body's
immune system (immunological tests).
Lymph nodes are part of the immune system. They are found in the
neck, behind the ears, in the armpits, and in the chest, belly, and groin. See
an illustration of
lymph
nodes
and the
immune
system
.
Lymph nodes in healthy people are usually hard to feel. However,
lymph nodes in the neck, armpit, or groin can get bigger and become tender.
Swollen lymph nodes usually mean an infection, but the swelling can also be
caused by a cut, scratch, insect bite, tattoo, a drug reaction, or
cancer.
There are several ways to do a lymph node biopsy. The lymph node
sample will be looked at under a microscope for problems.
- A fine-needle aspiration
biopsy puts a thin needle into the lymph node and removes cells to look
at. A needle biopsy is done to check the cause of a big lymph
node.
- A core needle biopsy uses a needle
fitted with a special tip. The needle goes through the skin to the lymph node
to take a sample of tissue about the size of a pencil lead.
- An
open biopsy makes a cut in the skin and removes the
lymph node. If more than one lymph node is taken, the biopsy is called a lymph
node dissection. Open biopsy and lymph node dissection let your doctor take a
bigger sample than a needle biopsy.