Serum Osmolality

Blood Osmolality Test, Osmolality Test

Why It Is Done

Serum osmolality is measured to:

  • Check the balance between the water and the chemicals dissolved in blood.
  • Find out if severe dehydration or overhydration is present.
  • Check to see if the hypothalamus is producing enough antidiuretic hormone (ADH).
  • Find the cause of seizures or coma. In severe cases, an imbalance between water and electrolytes in the body can cause seizures or coma.
  • Find out if a person has swallowed certain poisons, such as rubbing alcohol (isopropanol), wood alcohol (methanol), or antifreeze (ethylene glycol). Serum osmolality can also help find out how much of these poisons are present in the blood.

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Author: Maria G. Essig, MS, ELS
Ralph Poore
Last Updated: January 29, 2008
Medical Review: Anne C. Poinier, MD - Internal Medicine
Caroline S. Rhoads, MD - Internal Medicine
David C.W. Lau, MD, PhD, FRCPC - Endocrinology & Metabolism

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Topic Contents
 Test Overview
Arrow PointerWhy It Is Done
 How To Prepare
 How It Is Done
 How It Feels
 Risks
 Results
 What Affects the Test
 What To Think About
 References
 Credits