Renin Assay

Plasma Renin Activity (PRA) Test

Test Overview

A renin assay blood test is done to find the cause of high blood pressure (hypertension). Renin is an enzyme made by special cells in the kidneys. Renin works with aldosterone (a hormone made by the adrenal glands) and several other substances to help balance sodium and potassium levels in the blood and fluid levels in the body, which affects your blood pressure.

A renin test is often done at the same time as an aldosterone test. In some people, it may be normal to have high blood levels of both renin and aldosterone. If renin levels are low and aldosterone levels are high, a tumour may be present in the adrenal glands.

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Author:	Douglas Dana Jan Nissl, RN, BS	Last Updated: December 1, 2006
Medical Review:	Adam Husney, MD - Family Medicine Caroline S. Rhoads, MD - Internal Medicine David C.W. Lau, MD, PhD, FRCPC - Endocrinology & Metabolism
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