What Happens
Dupuytren's disease is often not noticed until it
becomes severe. The tissue between your skin and tendons, known as the palmar
fascia, becomes abnormally thick and fibrous. It is not yet clear what causes
this thickening.
There are three general phases of the disease:3
- Early. You may notice a
small knot on the palm or at the base of the fingers. There is no pulling or
contracture between the fingers and the
palm.
- Active. Dimpling appears on the skin
of the palm due to the growth of the thickened palmar fascia. Long, rope-like
cords and bands also develop in the fascia, stretching from the palm to one or
more fingers. The cord can sometimes be seen and felt.
- Advanced.
The thickened palmar fascia and cord cause a rigid, disabling
contracture
when the attached finger is drawn towards
the palm. Eventually you will not be able to flatten your palm on a table or
other even surface. Very severe forms of the disease result in an inability to
do routine tasks, such as using silverware.
The disease usually progresses slowly. It most often occurs after
age 50.4 Many people have a mild form that does not
cause significant problems. However, a rare form called Dupuytren's diathesis
occurs at an early age and progresses rapidly.
Dupuytren's disease develops in both hands in 40% of people with
the condition, and it most commonly affects the ring and small fingers.5
The goal of surgery for Dupuytren's disease is to control the
disease and to restore use of the fingers. Even with successful surgery,
thickened palm tissue may develop again in the same place or in a new area of
the hands. To maintain hand function, reoperation is necessary in some
individuals.