Age-Related Macular Degeneration

What Increases Your Risk

The major risk factors for age-related macular degeneration (AMD) include:

  • Older age. Age is the biggest risk factor for developing AMD. About 2% of people who are older than 50 have AMD. After age 75, up to 46% of people may have some form of it.2
  • A family history of the disease. You are much more likely to get AMD if a close relative has it.
  • Race. Whites appear to have a higher risk than blacks or Hispanics.
  • Smoking. People who smoke are about twice as likely to develop AMD than non-smokers. The risk appears to be higher for people who have been heavy smokers or who have smoked for a long time.2
  • One eye with wet AMD. Nearly half of people with wet AMD in one eye get wet AMD in the other eye within 5 years.1

Other risk factors for developing AMD may include:2

  • Deposits at the back of the eye called drusen. Eyes with large, soft drusen deposits are at a greater risk for developing abnormal blood vessels and wet AMD.
  • A diet high in saturated fat and cholesterol.
  • Low dietary intake of carotenoids, antioxidant vitamins, and zinc.

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Author: Alison Allen
Robin Parks, MS
Last Updated: October 8, 2007
Medical Review: Kathleen Romito, MD - Family Medicine
Carol L. Karp, MD - Ophthalmology
Donald Sproule, MD, CM, CCFP, FCFP - Family Medicine

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