Lead Poisoning

Symptoms

Lead poisoning usually does not cause symptoms until the level of lead in your blood is very high. Most lead poisoning comes from low levels of exposure over a long period of time. The major organ systems affected are the central nervous systemClick here to see an illustration., gastrointestinal (digestive) tractClick here to see an illustration., and the renal system (urinary tract)Click here to see an illustration..

Chronic lead exposure may cause the following symptoms.

General physical symptoms in children and adults (usually seen when lead poisoning levels are severe)

  • Stomachaches, cramping, constipation, or diarrhea
  • Nausea, vomiting
  • Persistent, unexplained fatigue
  • Headache
  • Muscle weakness
  • Higher rates of tooth decay

Children with chronic low blood lead levels who may not have obvious symptoms of lead poisoning may have learning problems and be smaller in size than children their age who do not have low to moderate levels of lead poisoning. A recent study showed that declines in IQ can even be seen in children with blood lead concentrations below 10 micrograms of lead per decilitre of blood (10 mcg/dL), the level of concern defined by the U.S. Centers for Disease Control and Prevention and the World Health Organization.10 Chronic exposure to lead may also cause behavioural problems in these children.

Behavioural symptoms in children

  • Irritability or aggressiveness
  • Hyperactivity, being easily distracted, impulsiveness
  • Learning problems
  • Lack of interest in play
  • Loss of appetite

Behavioural symptoms in adults

  • Irritability
  • Unexplained changes in mood or personality
  • Changes in sleep patterns
  • Inability to concentrate
  • Memory loss

Neurological symptoms (caused by effects of lead on the nervous system)

  • Poor coordination
  • Weakness in hands and feet
  • Headaches
  • Seizures
  • Paralysis
  • Coma

Diagnosing lead poisoning can be difficult because many other conditions cause similar symptoms.

Severe symptoms of acute lead poisoning can include seizures, unconsciousness, paralysis, or swelling in the brain. However, exposure to such a high level of lead is not common.1 If you experience these symptoms, seek emergency medical care.


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Author: Douglas Dana
Sydney Youngerman-Cole, RN, BSN, RNC
Last Updated: September 26, 2006
Medical Review: Michael J. Sexton, MD - Pediatrics
Tom Bailey, MD - Family Medicine
R. Steven Tharratt, MD, MPVM, FACP, FCCP - Pulmonology, Critical Care, Medical Toxicology

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 Topic Overview
 Cause
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 What Happens
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