Topotecan
Examples
Generic Name Brand Name Topotecan hydrochloride Hycamtin How It Works
Topotecan is an intravenous (IV) medication usually given in a dose based on body weight. The type and extent of a cancer determines the exact dose and schedule for administering this medication.
Why It Is Used
Topotecan is a topoisomerase inhibitor that stops the growth of cancer cells by preventing cell division. It is used to treat endometrial cancer, ovarian cancer, and cervical cancer.
How Well It Works
Topotecan is an effective antitumour medication. However, the type and extent of a cancer determines how effectively this medication slows or stops the growth of cancer cells in the body.
Side Effects
Side effects of topotecan include:
- Decreased white blood cell counts. Red blood cell counts and platelet counts can also be reduced.
- Nausea, vomiting, and loss of appetite.
- Diarrhea or constipation.
- Changes in liver function tests.
What To Think About
Topotecan should be administered only under the supervision of a medical oncologist.
Do not use this medication if you have:
- Kidney or liver disease.
- Chicken pox or shingles.
- Gout.
- Heart failure.
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| Author: | Kathe Gallagher, MSW Carrie Henley | Last Updated: February 21, 2007 |
| Medical Review: | Joy Melnikow, MD, MPH - Family Medicine Ross Berkowitz, MD - Obstetrics and Gynecology Andrew Swan, MD, CCFP, FCFP - Family Medicine | |
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| How It Works | |
| Why It Is Used | |
| How Well It Works | |
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| What To Think About | |