Examples
| Generic Name | Brand Name |
|---|
| amiodarone | Cordarone |
| disopyramide | Rythmodan |
| flecainide | Tambocor |
| procainamide | Procan |
| propafenone | Rythmol |
| quinidine | Biquin Durules |
| sotalol | Rylosol |
How It Works
Antiarrhythmic medicines work in various ways to return the heart
to its normal rhythm. These medicines stabilize heart rhythm by decreasing
abnormal firing of the heart's electrical system that causes the heart to beat
too fast or by slowing the electrical conduction through abnormal pathways.
Some antiarrhythmics also slow the heart rate by reducing the number of
impulses that can pass through the
atrioventricular (AV) node (amiodarone, sotalol).
Why It Is Used
Antiarrhythmic medicines are used to change an abnormal heart
rhythm to a regular rhythm and to prevent an abnormal heart rhythm.
How Well It Works
Antiarrhythmic medicines can effectively control or prevent
abnormal heart rhythms. There are many different types of antiarrhythmic
medicines. You may need to try different medicines to see which one works best
for you.
Side Effects
Some antiarrhythmic medicines may increase the risk of developing a
more rapid, abnormal heart rate problem (ventricular tachycardia or ventricular
fibrillation), especially for those people with a poorly functioning left
ventricle. Close monitoring while taking these medicines is important.
Side effects of antiarrhythmics include:
- Chest pain.
- Slow
heartbeat.
- Palpitations.
- Fatigue.
- Headache.
- Dizziness.
- Nausea
and vomiting.
- Unusual taste in the mouth.
- Stomach
pain.
- Constipation or diarrhea.
- Difficulty
breathing.
- Rash.
- Vision problems.
- Urinary
retention in men.
- Blue tinge to the skin (with amiodarone).
The United States Food and Drug Administration (FDA) recently
issued warnings about the medicine amiodarone (Cordarone). People taking this
medicine should be aware that it may cause serious side effects that can lead
to death, including lung damage, liver damage, and more severe heartbeat
problems. Amiodarone is typically used for people who have severe symptoms when
other medicines have failed. The FDA recommends that you talk to your doctor if
you have any side effects or any concerns about taking amiodarone.1
See Drug Reference for a full list of side effects. (Drug Reference
is not available in all systems.)
What To Think About
You should learn to
take
your pulse
if you are taking an antiarrhythmic medicine. Notify your
doctor if your heart rhythm becomes too slow (less than 50 beats per minute) or
irregular while you are taking an antiarrhythmic medicine.
Complete the
new medication information form (PDF)
(What is a PDF document?)
to help you understand this medication.