Allylamines for ringworm of the skin

Examples

Cream or gel (topical, applied directly to the skin)

Generic Name	Brand Name
naftifine hydrochloride	Naftin
terbinafine hydrochloride	Lamisil

Pills (oral)

Generic Name	Brand Name
terbinafine hydrochloride	Lamisil

Allylamines are a class of antifungals used to treat ringworm of the skin.

Terbinafine and naftifine creams and gels are applied to infected areas of the skin. Naftifine cream is available without a prescription. Terbinafine is not available in Canada without a prescription. You apply these creams 1 to 2 times a day for up to 4 weeks.

Terbinafine pills are taken twice a day for about 2 weeks.

How It Works

Allylamines kill fungi.

Why It Is Used

Allylamines are used to treat ringworm of the skin. Creams are usually used first, and you can buy naftifine creams without a prescription. If an antifungal cream does not clear up the infection or if the infection is widespread or severe, your doctor may prescribe antifungal pills.

How Well It Works

Allylamines are an effective treatment for ringworm of the skin.

Terbinafine works quickly, and longer treatment times are not necessary. People are more likely to complete a shorter treatment.

Side Effects

Side effects are rare when you use allylamine creams to treat ringworm.

Side effects of pills may include:

• Stomach upset.
• Headaches.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

If you are taking antifungal pills, your doctor may monitor your blood count and liver function during treatment to watch for any bad side effects. This may not be necessary in people who are otherwise healthy.

What To Think About

• Women who are nursing a baby should not take allylamine pills.
• Do not drink alcohol while taking terbinafine pills, because this may increase the risk of liver damage.
• Allylamine pills should not be taken with some other medicines, such as an excessive amount of acetaminophen (Tylenol). Let your doctor know what other medicines you are taking.

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Author:	Douglas Dana Maria G. Essig, MS, ELS	Last Updated: June 1, 2007
Medical Review:	Kathleen Romito, MD - Family Medicine Randall D. Burr, MD - Dermatology Andrew Swan, MD, CCFP, FCFP - Family Medicine
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