Examples
| Generic Name | Brand Name |
|---|
| lindane | Hexit, PMS-Lindane |
Lindane is available over-the-counter as a lotion or shampoo to
treat
lice. Treatment needs to be repeated 1 week after the
first dose.
Lindane can cause serious side effects if you do not use it
exactly as directed. Lindane lotion or cream (for pubic lice)
should be applied and rubbed into cool, dry skin and hair. If it is applied to
warm, moist skin (such as right after a bath or shower), it will be absorbed
quickly by the skin and could cause side effects. The lotion is left on for 8
to 12 hours and then washed off.
Lindane shampoo (for head lice) is applied to dry hair and
thoroughly rubbed into the hair and scalp. It is left on for 4 minutes, worked
into a lather with a small amount of water, and rinsed well.
How It Works
Lindane kills lice but does not kill lice eggs (nits). Newly
hatched lice are killed during the second treatment.
Why It Is Used
Lindane may be used when other products fail to get rid of lice or
when a person cannot use any of the other products. The shampoo may be used to
treat head lice, and the lotion may be used to treat pubic lice.
Lindane was the drug of choice for treating lice for many years,
but now it is not the preferred treatment. Permethrin (Nix or Kwellada-P Creme
Rinse) works better and is less likely to cause side effects.
Lindane should not be used by pregnant women, nursing mothers,
children less than 2 years old, people who have seizure disorders, or people
who have certain skin diseases that may increase the likelihood that the
product will be absorbed into their skin.
How Well It Works
Lindane can be effective at treating head and pubic lice.
In some countries, such as the United Kingdom and United States,
lice have become resistant to lindane, and the treatment is not as
effective.1, 2
Side Effects
When used as directed, lindane is safe and has few side effects.
However, it is easily absorbed into the skin and can cause negative side
effects when it is not used properly. If lindane is left on the skin too long,
used repeatedly, or eaten, it can cause nervous system side effects, such as
seizures, especially in young children.
See Drug Reference for a full list of side effects. (Drug Reference
is not available in all systems.)
What To Think About
Use this product exactly as labelled. Although most of the side
effects reported from this product are from misuse and overuse, it does contain
potentially harmful toxins.3, 4
Lindane is no longer the treatment of choice for head and pubic
lice because it is more likely to cause side effects than permethrin (Nix or
Kwellada-P Creme Rinse).
If you are going to use lindane on a small child, dress the child
in clothing that covers the entire body and be sure he or she does not lick his
or her skin. Put socks on the child's hands to prevent licking of the hands. If
the child cannot be prevented from licking the skin, permethrin or sulfur
(other lice treatment products) should be used.
Overuse of lice medicines (such as reapplying the lotion when only
a single use is recommended) can irritate the skin and may increase the risk of
side effects from some products. It is common for itching to persist for 7 to
10 days after treatment. Itching is not a reason to treat the person
again.
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