Examples
| Generic Name | Brand Name |
|---|
| acyclovir | Zovirax |
| famciclovir | Famvir |
| valacyclovir hydrochloride | Valtrex |
Antiviral medications can be taken by mouth (orally) or given by
injection into a vein (intravenous, or IV). Acyclovir is the antiviral
medication used most often to treat
chicken pox (varicella). However, other antivirals may
be used.
Antiviral eye ointments are also available. They can be used on
your eyes to treat chicken pox blisters.
How It Works
Antiviral medications stop the growth of the chicken pox
(varicella-zoster) virus.
Why It Is Used
Antiviral medications may be given to people who have been in
contact with someone who has chicken pox. Antiviral medications are generally
given to people who are more likely to become seriously ill or develop
complications from chicken pox. These medications need to be started within 24
hours of the first signs of chicken pox rash.
Oral antivirals may safely be given to people who:
- Have long-term illnesses, such as skin or lung
diseases.
- Are receiving short-term
corticosteroid medication, such as people being
treated for
asthma.
- Are receiving long-term treatment
with certain medications containing salicylates, such as people with
arthritis.
Intravenous antivirals are usually recommended for:
- People with
impaired immune systems.
- Pregnant women
with serious complications of chicken pox.
- Babies born early or
babies who have a low birth weight and whose mother had chicken pox.
Antiviral eye ointment is recommended for people who have
chicken pox blisters in their eyes.
These medications are usually NOT
recommended for:
- Healthy people as a way to prevent them from
having chicken pox if they have been exposed to the
illness.
- Pregnant women unless they have complications of
chicken pox.
Parents of an otherwise healthy child may want their child to have
an antiviral medication to shorten the time the child is ill or reduce the
severity of symptoms. However, parents may choose not to give antiviral
medications to their otherwise healthy child because his or her symptoms are
not severe or the illness is not causing problems for the family.
Antiviral medications may work best to protect family members of a
person with chicken pox from getting chicken pox.
- Often the first person in a family to get
chicken pox is not able to get an antiviral medication soon enough (within 24
hours of the first sign of rash).
- Other family members have time to
look for the first signs of chicken pox and watch for the chicken pox rash. At
the first sign of rash, they can take an antiviral medication. Other family
members are also more likely to have severe symptoms because they have been in
close contact with someone who has chicken pox and have been exposed to higher
concentrations of the virus.
How Well It Works
Antiviral medications may shorten the length of illness from
chicken pox, cause fewer blisters to form, and help blisters heal faster.
Antiviral medications may reduce by 20% the number of days a person
is sick with chicken pox (for example, from 5 days to 4) and the number of
chicken pox spots (for example, from 200 spots to 160).
It is not known whether antiviral medications reduce the chance of
developing complications of chicken pox. Antiviral medications may reduce the
complications of chicken pox, such as varicella
pneumonia, in people with impaired immune
systems.
Side Effects
Antiviral medications have few side effects. They include:
- Headache or feelings of general illness
(malaise).
- Nausea and vomiting.
- Diarrhea or
constipation. This is rare.
- Kidney problems in people who receive
large doses of acyclovir by rapid injection into a vein. This is rare.
The effect of antiviral medications on pregnant women and their
fetuses is not known.
The effect of antiviral medications on
immunity to chicken pox is not known.
See Drug Reference for a full list of side effects. (Drug Reference
is not available in all systems.)
What To Think About
Consider the following when deciding whether to treat a family
member with antiviral medications:
- Antiviral medications are expensive. But the cost of medication is usually covered under provincial health plans or private health insurance.
- Treatment with antiviral medications may
reduce the length of time you can pass the chicken pox virus to other
people.
- It is not clear whether antiviral medications reduce lost
time from work, school, or day care.
Acyclovir (Zovirax) is the most prescribed antiviral medication. It
has fewer side effects than the other antiviral medications. However, it does
not reduce itching, nor does it stop the spread of the chicken pox virus from
one person to another.
People who take acyclovir need to drink extra liquids to prevent
kidney problems. People who have kidney problems need to take a lower dose of
acyclovir.
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