Who is affected by necrotizing enterocolitis

Necrotizing enterocolitis is the most common gastrointestinal emergency among newborns, usually those who are born prematurely. It mainly affects premature infants who weigh less than 1500 g (3.3 lb). One baby out of 10 with a birth weight less than 1500 g (3.3 lb) has it.1

Being born prematurely and at a low birth weight puts an infant at risk for necrotizing enterocolitis.

Other possible risk factors include:2

  • Being exposed to bacteria. A newborn who has intestinal damage may be more susceptible to infection.
  • Having more red blood cells than needed (polycythemia).
  • Being exposed to cocaine or methamphetamine before birth.
  • Having sepsis and/or low blood pressure (hypotension).
  • Having patent ductus arteriosis, a congenital heart defect.


Author: Debby Golonka, MPHLast Updated: July 20, 2007
Medical Review: Michael J. Sexton, MD - Pediatrics
Jennifer Merchant, MD - Neonatal-Perinatal Medicine
Anne C. Poinier, MD - Internal Medicine

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