Health problems associated with adult obesity
Adults with obesity are more likely to have certain health problems than adults who are not obese. These problems include the following.
Heart disease and cardiovascular problems
People who are obese have an increased risk of:1
- Heart disease, including coronary artery disease, heart attack, heart failure, angina, and an abnormal heartbeat.
- High blood pressure. High blood pressure in obese men may in turn increase the risk of kidney cancer.2
- High levels of cholesterol and triglycerides in the blood, as well as lower levels of "good" HDL cholesterol.
- Stroke.
Diabetes
People who are obese are more likely to develop insulin resistance, which can lead to type 2 diabetes.1 One study has noted that men and women who have a body mass index (BMI) over 35 are approximately 20 times more likely to develop diabetes over a 10-year period than people with a normal weight (a BMI of 18.5 to 24.9).3
The risk of type 2 diabetes increases as BMI increases. People who have a large percentage of body fat in the abdominal area—greater than 94 cm (37 in.) in men and greater than 80 cm (31.5 in.) in women—are at increased risk for type 2 diabetes, even if their BMIs are within the normal range.4 Weight gain of more than 8 kg (18 lb) after age 21 in men or 10 kg (22 lb) after age 18 in women further increases the risk for type 2 diabetes.5
Cancer
People who are obese may be at greater risk for different types of cancer, including:1, 6
- Endometrial cancer.
- Breast cancer.
- Kidney cancer.
- Colorectal cancer.
- Gallbladder cancer.
- Prostate cancer.
- Esophageal cancer.
Digestive problems
People who are obese may have more digestive problems.7
- Women who are obese have twice the risk of developing gallstones as women of normal weight, and women who are extremely obese (a BMI over 45) have 7 times the risk.
- A few studies report that people who are obese and who develop pancreatitis have worse outcomes than people of normal weight.
- Obesity is associated with liver problems such as an enlarged liver (hepatomegaly), a fatty liver (steatosis), or cirrhosis.
- Symptoms of gastroesophageal reflux disease (GERD) are more common in people who are obese than in people of normal weight.
Breathing problems
People who are obese may have difficulty breathing.
- They are more likely to have sleep apnea. Although about 1% to 4% of all people have breathing problems while sleeping, about 24% of overweight men and 9% of overweight women do.8
- Obesity is associated with a higher prevalence of asthma.1
- People who are obese tend to take smaller or shallower breaths (pickwickian syndrome). These small, gasping breaths may not get as much oxygen into the blood as needed, leaving them always tired. Pickwickian syndrome can eventually lead to heart problems.
Arthritis
People who are obese have a greater risk of developing arthritis.
- Extra weight puts more stress on the joints than normal, especially in the legs and lower back.
- For every 1 kg (2 lb) increase in weight, the risk of developing arthritis increases 9% to 13%.1
Sex hormone problems
Obesity is associated with:
- Problems with becoming pregnant (infertility).7
- Irregular menstrual periods.7
- Increased risk of death for mother and baby.1
- Increased risk of birth defects, especially neural tube defects.1
Other Problems
- Kidney disease.9
| Author: | Douglas Dana Caroline Rea, RN, BS, MS | Last Updated: July 27, 2007 |
| Medical Review: | Anne C. Poinier, MD - Internal Medicine Caroline S. Rhoads, MD - Internal Medicine Matthew I. Kim, MD - Endocrinology & Metabolism David C.W. Lau, MD, PhD, FRCPC - Endocrinology & Metabolism | |
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