Medicines that can cause pancreatitis

In rare cases, medicines may cause inflammation of the pancreas (pancreatitis). These include:

  • Some antibiotics (such as metronidazole, tetracycline, sulfamethoxazole and trimethoprim, and nitrofurantoin).
  • Some medicines that suppress the immune system (such as 6-mercaptopurine and azathioprine).
  • Some medicines used to treat high blood pressure (such as ACE inhibitors).
  • 5-aminosalicylic acid (used to treat inflammatory bowel disease).
  • Some diuretics.
  • Corticosteroids.
  • Estrogen.
  • Valproic acid (used to treat seizure disorders).
  • Certain general anesthetics.
  • Antidepressants, such as venlafaxine (Effexor).


Author: Monica RhodesLast Updated: August 16, 2007
Medical Review: Kathleen Romito, MD - Family Medicine
Anne C. Poinier, MD - Internal Medicine
Brent Shoji, MD - General Surgery

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