Advantages and disadvantages of hormone injections for birth control

The following table lists the advantages and disadvantages of using the Depo-Provera injection birth control method.

Depo-Provera (progestin-only injection)

Advantages

Disadvantages

  • Using Depo-Provera for 2 or more years can cause bone loss, which may not be fully reversible after stopping the medication. Bone thinning can lead to osteoporosis in later life. This concern may be greatest during the teen years, when young women should be building bone mass.1 Talk to your health professional about whether the benefits of long-term use outweigh your risks and how you can protect your bones with daily calcium and regular weight-bearing exercise, such as walking or running.2
  • Often causes irregular spotting
  • Causes slight weight gain
  • Fertility may not return for 6 to 8 months after stopping the medication
  • May decrease levels of HDL ("good") cholesterol
  • Provides no protection against sexually transmitted infections (STIs)
  • May increase the risk of chlamydia or gonorrhea infection among women who are sexually exposed to these bacteria. (Depo-Provera users who have any risk of exposure to STIs are advised to use condoms.3)


Author: Merrill Hayden
Carrie Henley
Last Updated: August 16, 2006
Medical Review: Adam Husney, MD - Family Medicine
Joy Melnikow, MD, MPH - Family Medicine
Kirtly Jones, MD - Obstetrics and Gynecology
Femi Olatunbosun, MB, FRCSC - Obstetrics, Gynecology and Reproductive Medicine

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