Liquid-based collection methods for cervical cell evaluation
Liquid-based methods for collecting cervical cells and preparing them for laboratory evaluation are now becoming more available.
A sample of cervical cells is collected during a Pap test, and the cells are then rinsed in a liquid vial instead of being smeared on slides. The vials are taken to the laboratory, and a thin layer of the specimen is put on slides for microscopic examination. Only a small portion of the sample is used for the slide, so the remainder of the cell sample can be used for any additional testing, such as human papillomavirus (HPV) testing.
Some studies show that this method may be more sensitive in identifying abnormal cervical cell changes. However, these methods can produce false-positive results just like standard Pap tests. Not all laboratories provide this testing, but liquid-based methods are becoming more widely used. These methods cost more than standard Pap testing.
| Author: | Shannon Erstad, MBA/MPH Carrie Henley | Last Updated: April 10, 2007 |
| Medical Review: | Joy Melnikow, MD, MPH - Family Medicine Anne C. Poinier, MD - Internal Medicine Barbara S. Apgar, MD, MS - Family Medicine, Women's Health Ross Berkowitz, MD - Obstetrics and Gynecology Deborah A. Penava, BA, MD, FRCSC, MPH - Obstetrics and Gynecology | |
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