Disseminated intravascular coagulation (DIC) and placenta abruptio

Disseminated intravascular coagulation (DIC) is a serious blood-clotting problem. It occurs in about 10% of women with placenta abruptio. Most of the time, this is when there is severe bleeding or a fetus dies from the abruption.1

In DIC, the body's natural ability to regulate blood clotting does not function as it should. This causes the blood's clotting cells (platelets) to clump together. These clumps clog small blood vessels throughout the body. This excessive clotting can damage organs, destroys blood cells, and depletes the supply of platelets and other clotting factors so that the blood is no longer able to clot normally. This often causes widespread bleeding, both internally and externally.

Transfusions of blood and other blood-clotting products, such as platelets, are usually required when DIC complicates labour and delivery.



Author: Kathe Gallagher, MSW
Carrie Henley
Last Updated: May 15, 2006
Medical Review: Joy Melnikow, MD, MPH - Family Medicine
Tom Bailey, MD - Family Medicine
William Gilbert, MD - Perinatology

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