Risk factors for placenta abruptio

The causes of placenta abruptio are not well-understood, and some women develop it without any identifiable cause. However, you can reduce your risk by treating or avoiding some of the known risk factors that have been linked to placenta abruptio.

Your risk may be increased if you:

  • Have high blood pressure (140/90 mm Hg or higher), whether it is chronic or has been caused by the pregnancy (pregnancy-induced hypertension or pre-eclampsia). High blood pressure is the most common risk factor linked to placenta abruptio.1
  • Have had a placental abruption before. If you have had more than one abruption, your risk is greater.2
  • Smoke cigarettes. The more you smoke, the greater your risk of abruption. Up to 25 of every 100 placental abruptions are linked to cigarette smoking.3
  • Use cocaine. This puts you at high risk for abruption.4
  • Have a physical injury to your uterus, such as from a motor vehicle accident or from a direct blow to the abdomen.5
  • Have had a premature rupture of membranes (PROM) for more than 24 hours. Also having an infection in the uterus raises this risk.1
  • Have a history of uterine problems, such as a uterine fibroid where the placenta is attached.4
  • Have a blood-clotting disorder that makes your blood more likely to clot. This is a disorder that can run in families, or is inherited.4

Risk factors that slightly increase your abruption risk include:



Author: Kathe Gallagher, MSW
Carrie Henley
Last Updated: May 15, 2006
Medical Review: Joy Melnikow, MD, MPH - Family Medicine
Tom Bailey, MD - Family Medicine
William Gilbert, MD - Perinatology

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