Medicines that may cause chest pain

Medicines usually do not cause chest pain. However, some medicines, such as ASA, ibuprofen, and some antibiotics may cause stomach acid to back up (reflux) into the esophagus, causing pain or discomfort behind the breastbone, in the centre of the chest (heartburn).

The use of illegal drugs, especially cocaine and amphetamines, may cause a rapid heart rate and chest pain.

If a chest pain occurs after you have begun a new medicine:

  • Call the doctor who prescribed the medicine to determine whether you should stop taking the medicine or take a different one. An appointment may not be necessary. Do not take another dose of the medicine until you have spoken to your doctor.
  • If you are taking a non-prescription medicine, stop taking it. Call your doctor if you feel you need to continue taking the medicine.


Author: Jan Nissl, RN, BSLast Updated: June 22, 2007
Medical Review: William M. Green, MD - Emergency Medicine
H. Michael O'Connor, MD - Emergency Medicine

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