Medications that can cause abdominal pain

Many prescription and non-prescription medications can cause abdominal pain by irritating the stomach lining, which can cause heartburn or ulcer-like symptoms. Medications that may cause these symptoms include:

  • Non-steroidal anti-inflammatory drugs (NSAIDs):
    • ASA.
    • Ibuprofen, such as Advil.
    • Naproxen sodium, such as Anaprox.
  • Corticosteroids, such as prednisone.
  • Alcohol.

Other medications can cause abdominal cramping, diarrhea, or constipation. Medications that may cause these symptoms include:

  • Antidiarrheals, which can cause constipation and abdominal cramping.
  • Laxatives, which can cause diarrhea and abdominal cramping.
  • Antibiotics, such as ampicillin, amoxicillin, tetracycline, cefuroxime, erythromycin, and clindamycin, which can cause abdominal cramping and burning pain.
  • Iron supplements, which can cause constipation, burning pain, and black stools.
  • Mylanta or Maalox, which can cause diarrhea and abdominal cramping.

Your health professional may be able to prescribe other medications if you are having abdominal pain caused by a medication. There also may be ways to take a medication that will decrease the chance that it will cause abdominal pain.



Author: Jan Nissl, RN, BSLast Updated: April 9, 2007
Medical Review: William M. Green, MD - Emergency Medicine
Jerome B. Simon, MD, FRCPC, FACP - Gastroenterology

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