Use of acetaminophen in young children

Acetaminophen, such as Anacin 3, Panadol, Tempra, or Tylenol, helps reduce fever and relieve pain. It does not reduce swelling, as do non-steroidal anti-inflammatory drugs (NSAIDs) such as ASA and ibuprofen, but it also does not cause stomach upset and other side effects.

Acetaminophen is the preferred medication to reduce fever in children. If your child has a fever of 39°C (102°F) or higher and is uncomfortable, consider using acetaminophen to lower the fever.

Be sure to follow these medication precautions.

  • Call your health professional or pharmacist if you are unsure of the right dose for your child.
  • Do not use acetaminophen if your child is allergic to it.
  • Read all the instructions on the medication bottle and box carefully before giving your child any medication.
  • Follow all instructions on the medication bottle and box. The correct dose and timing of the dose are important for the medication to work well.

Talk to your doctor before you give acetaminophen to a baby who is 3 months of age or younger. This is to make sure a young baby's fever is not a sign of a serious illness. The exception is if your baby has just had an immunization. Fevers sometimes occur as a reaction to immunizations. After immunizations, you can give your baby acetaminophen.

Dosage: Give acetaminophen every 4 hours as needed. Do not give more than five doses in a 24-hour period. Dosages are based on the child's weight regardless of whether oral or rectal products are used.

Acetaminophen products include acetaminophen drops, acetaminophen syrup, chewable acetaminophen, or rectal suppositories. These products come in standard concentrations for children.

Child's weight in kilogramsChild's weight in poundsDosage

2.7 to 4.0

6.0 to 9.0

40 mg to 60 mg

4.5 to 5.5

10.0 to 12.0

60 mg to 80 mg

5.5 to 7.0

13.0 to 15.0

80 mg to 100 mg

7.0 to 9.0

16.0 to 20.0

100 mg to 120 mg

9.5 to 11.0

21.0 to 24.0

120 mg to 160 mg

11.0 to 13.5

25.0 to 30.0

160 mg to 200 mg

14.0 to 16.5

31.0 to 36.0

200 mg to 240 mg

6.5 to 19.0

37.0 to 42.0

240 mg to 280 mg

19.5 to 21.0

43.0 to 47.0

280 mg to 320 mg

21.5 to 25.0

48.0 to 55.0

320 mg to 380 mg

25.5 to 34.0

56.0 to 75.0

380 mg to 500 mg

34.5 to 40.5

76.0 to 89.0

500 mg to 600 mg

more than 40.5

more than 90.0

650 mg (adult dose)

Side effects of acetaminophen are rare.

  • Nausea and rash are the most common.
  • High doses of acetaminophen can contribute to liver damage.

Do not give your child acetaminophen if he or she has:

  • Kidney disease.
  • Liver disease.


Author: Jan Nissl, RN, BSLast Updated: June 22, 2007
Medical Review: Michael J. Sexton, MD - Pediatrics
Thomas Emmett Francoeur, MDCM, CSPQ, FRCPC - Pediatrics

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