Family history of heart disease

People who have family members with coronary artery disease (CAD) are at an increased risk of developing CAD for several reasons. A tendency to develop certain risk factors, such as high cholesterol and high blood pressure, may be related to specific inherited genes. Genes are passed on from parent to child and are like the blueprints of the body: They are a code that determines how our bodies are made and how they function.

When a close family member (parent or sibling) has CAD, it may be due to an inherited lipid disorder that can contribute to atherosclerosis. Although family-related behaviours also contribute to the risk of developing CAD, researchers are still working to understand exactly why CAD runs in families.

Behaviour or genetics?

In addition to inherited factors, there is probably a large environmental component to the increased risk seen in some families. People who smoke expose their family members to second-hand smoke, increasing the risk of heart disease in their family members. Children of parents who smoke are more likely to smoke than children of non-smokers. Dietary habits may also play a role. Families who eat fatty diets are more likely to develop CAD than those who eat more balanced diets. Addressing each of these family-related behaviours may greatly reduce your chances of developing CAD.



Author: Douglas Dana
Robin Parks, MS
Last Updated: September 21, 2007
Medical Review: Anne C. Poinier, MD - Internal Medicine
Caroline S. Rhoads, MD - Internal Medicine
Stephen Fort, MD, MRCP, FRCPC - Interventional Cardiology
Robert A. Kloner, MD, PhD - Cardiology
Ruth Schneider, MPH, RD - Diet and Nutrition

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