Hypoxia occurs when the
cornea does not get enough oxygen. It is the most
common complication of contact lens wear, especially extended-wear
lenses.
The cornea has no blood supply of its own, so it gets oxygen only
from tears and directly from the atmosphere. A contact lens reduces the oxygen
supply to the cornea, making the cornea swell. Wearing contacts overnight
further decreases the amount of oxygen that gets to the cornea.
Gas-permeable hard contact lenses have almost eliminated some
once-common problems, such as over wearing syndrome and corneal clouding;
still-common problems include hazy vision caused by mild corneal swelling
(edema) or warping. Over time, corneal hypoxia may cause serious problems with
the cornea.